Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985146 | 0.94 | MAPT (0.67) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30984714 | 0.93 | MAPT (0.64) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30984960 | 0.90 | MAPT (0.72) | MAPTALDH1A1LMNAGPR119SMN1; SMN2 | |
| SCHEMBL30985145 | 0.87 | MAPT (0.69) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30722421 | 0.87 | MAPT (0.78) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30981045 | 0.87 | MAPT (0.60) | MAPTALDH1A1LMNAGPR119SMN1; SMN2 | |
| SCHEMBL12005014 | 0.86 | MAPT (0.69) | MAPTALDH1A1LMNAGPR119SMN1; SMN2 | |
| SCHEMBL28925340 | 0.85 | MAPT (0.68) | MAPTALDH1A1LMNAGPR119SMN1; SMN2 | |
| SCHEMBL4295931 | 0.85 | MAPT (0.67) | MAPTALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL4295926 | 0.85 | MAPT (0.67) | MAPTALDH1A1LMNASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |