Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24437049 | 1.00 | HDAC1 (0.47) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL22516670 | 0.94 | HDAC1 (0.45) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL30985386 | 0.89 | ESR1 (0.42) | — | |
| SCHEMBL22500092 | 0.89 | ESR1 (0.42) | — | |
| SCHEMBL22516716 | 0.88 | TACR1 (0.42) | — | |
| SCHEMBL24437127 | 0.87 | TACR1 (0.36) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL22516712 | 0.85 | TTR (0.42) | — | |
| SCHEMBL30985341 | 0.85 | TTR (0.42) | — | |
| SCHEMBL22500198 | 0.84 | TACR1 (0.37) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL22500243 | 0.83 | TACR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113660932-B | Phenyl derivatives having pendant alkyl and alkenyl extensions and pharmaceutical compositions comprising the same | 景凯生物科技股份有限公司 | 2024-07-12 | — | — | CN | disclosed |