Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 13/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22547843 | 0.95 | BRD4 (0.42) | HSP90AA1HSP90AB1LIPE | |
| SCHEMBL22548022 | 0.94 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1LIPE | |
| SCHEMBL15526006 | 0.93 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1LIPEKCNH2HRH3 | |
| SCHEMBL22541155 | 0.93 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1 | |
| SCHEMBL15525661 | 0.89 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1LIPEKCNH2HRH3 | |
| SCHEMBL22541191 | 0.89 | BRD4 (0.48) | HSP90AA1HSP90AB1HRH3 | |
| SCHEMBL15525678 | 0.89 | BRD4 (0.41) | HSP90AA1HSP90AB1LIPEKCNH2HRH3 | |
| SCHEMBL15525676 | 0.88 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1 | |
| SCHEMBL28129627 | 0.87 | KDM4E (0.41) | HSP90AA1HSP90AB1 | |
| SCHEMBL30985916 | 0.86 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113939516-B | Methods and compositions for targeting protein degradation | 珃诺生物医药科技(杭州)有限公司 | 2024-07-16 | — | — | CN | disclosed |