Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30986150 | 0.86 | CHRM2 (0.41) | HTR2CSIGMAR1CDC7STAT3SMN1; SMN2 | |
| SCHEMBL223608 | 0.73 | MEN1 (0.54) | SIGMAR1SMN1; SMN2POLBALOX15L3MBTL1 | |
| SCHEMBL28989093 | 0.72 | CDC7 (0.37) | HTR2CHTR2ACDC7L3MBTL1KDM4E | |
| SCHEMBL256336 | 0.72 | HTR2A (0.43) | HTR2CHTR2AHTR2BSIGMAR1STAT3 | |
| SCHEMBL27889514 | 0.71 | STAT3 (0.50) | HTR2CHTR2ASTAT3POLBALOX15 | |
| SCHEMBL29949377 | 0.71 | SLC22A12 (0.47) | CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL7691682 | 0.70 | STAT3 (0.49) | HTR2CHTR2ASTAT3POLBALOX15 | |
| SCHEMBL30210508 | 0.70 | STAT3 (0.49) | HTR2CHTR2ASTAT3POLBALOX15 | |
| SCHEMBL12905336 | 0.69 | HTR2A (0.41) | HTR2CHTR2AHTR2BSIGMAR1STAT3 | |
| SCHEMBL18361819 | 0.69 | NOTUM (0.60) | STAT3CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412113-B | Amino oxazinamides | 豪夫迈·罗氏有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-113412113-B | Amino oxazinamides | 豪夫迈·罗氏有限公司 | 2024-07-26 | — | — | CN | disclosed |