Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.51 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24878972 | 0.93 | PTPN11 (0.52) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24879021 | 0.93 | PTPN11 (0.50) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24879289 | 0.91 | PTPN11 (0.51) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24879146 | 0.90 | PTPN11 (0.52) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24878899 | 0.90 | PTPN11 (0.52) | PTPN11MAPK3MAPK1 | |
| SCHEMBL27453103 | 0.90 | PTPN11 (0.54) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24879025 | 0.89 | PTPN11 (0.50) | PTPN11MAPK3MAPK1 | |
| SCHEMBL31723339 | 0.88 | PTPN11 (0.51) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24879043 | 0.88 | PTPN11 (0.52) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24878865 | 0.88 | PTPN11 (0.55) | PTPN11MAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147703-A1 | SHP2 INHIBITOR AND USES THEREOF | 주식회사 카나프테라퓨틱스 | 2024-07-11 | — | — | WO | disclosed |