Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 19/20 | 0.51 |
| ▸ | CDK4 | P11802 | 4/20 | 0.47 |
| ▸ | CCND3 | P30281 | 4/20 | 0.47 |
| ▸ | CCNK | O75909 | 1/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | CCNH | P51946 | 1/20 | 0.47 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24879100 | 0.89 | PTPN11 (0.51) | PTPN11CDK4CCND3CCNKCCNE2 | |
| SCHEMBL30987288 | 0.87 | PTPN11 (0.54) | PTPN11CDK4CCND3CCNKCCNE2 | |
| SCHEMBL30987307 | 0.86 | PTPN11 (0.50) | PTPN11CDK4CCND3CCNKCCNE2 | |
| SCHEMBL30987358 | 0.86 | PTPN11 (0.41) | PTPN11CDK4CCND3CCNKCCNE2 | |
| SCHEMBL30987333 | 0.86 | PTPN11 (0.57) | PTPN11MAPK3MAPK1 | |
| SCHEMBL31723356 | 0.84 | PTPN11 (0.51) | PTPN11CDK4CCND3MAPK3MAPK1 | |
| SCHEMBL27454330 | 0.83 | PTPN11 (0.53) | PTPN11CDK4CCND3MAPK3MAPK1 | |
| SCHEMBL27461818 | 0.82 | PTPN11 (0.43) | PTPN11CDK4CCND3CCNKCCNE2 | |
| SCHEMBL27453044 | 0.81 | PTPN11 (0.67) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24879156 | 0.80 | PTPN11 (0.53) | PTPN11MAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147703-A1 | SHP2 INHIBITOR AND USES THEREOF | 주식회사 카나프테라퓨틱스 | 2024-07-11 | — | — | WO | disclosed |