Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23500668 | 1.00 | IDO1 (0.46) | IDO1ABCB1TSHRALOX15ATM | |
| SCHEMBL29760886 | 1.00 | IDO1 (0.46) | IDO1ABCB1TSHRALOX15ATM | |
| SCHEMBL23046236 | 1.00 | IDO1 (0.46) | IDO1ABCB1TSHRALOX15ATM | |
| SCHEMBL23024477 | 0.88 | IDO1 (0.33) | IDO1ABCB1TSHRKDM4E | |
| SCHEMBL23024475 | 0.88 | IDO1 (0.33) | IDO1ABCB1TSHRKDM4E | |
| SCHEMBL29892167 | 0.87 | HDAC2 (0.39) | IDO1GPR119HDAC1 | |
| SCHEMBL24672643 | 0.87 | HDAC2 (0.39) | IDO1GPR119HDAC1 | |
| SCHEMBL23046238 | 0.87 | HDAC2 (0.39) | IDO1GPR119HDAC1 | |
| SCHEMBL23046308 | 0.87 | HDAC2 (0.41) | IDO1GPR119HDAC1 | |
| SCHEMBL29891302 | 0.87 | HDAC2 (0.41) | IDO1GPR119HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024147703-A1 | SHP2 INHIBITOR AND USES THEREOF | 주식회사 카나프테라퓨틱스 | 2024-07-11 | — | — | WO | disclosed |