SCHEMBL30987477

SCHEMBL30987477

CCC(C)C=Cc1ccc(Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.44
NOS1 P29475 2/20 0.44
NOS2 P35228 2/20 0.44
AHR P35869 1/20 0.42
CYP1A2 P05177 1/20 0.39
KCNH2 Q12809 2/20 0.39
PTGS2 P35354 2/20 0.39
ALOX5 P09917 1/20 0.39
PTGS1 P23219 1/20 0.39
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
HTT P42858 1/20 0.38
FBP1 P09467 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18175092 0.82 AHR (0.41) NOS3NOS1NOS2AHRCYP1A2
SCHEMBL16874337 0.79 MEN1 (0.50) AHRCYP1A2GAAHSD17B10MEN1
SCHEMBL489023 0.79 MEN1 (0.50) AHRCYP1A2GAAHSD17B10MEN1
SCHEMBL10131184 0.79 AHR (0.48) AHRCYP1A2PTGS2ALOX5PTGS1
SCHEMBL9967711 0.79 AHR (0.48) AHRCYP1A2PTGS2ALOX5PTGS1
SCHEMBL14465008 0.79 AHR (0.48) AHRCYP1A2PTGS2ALOX5PTGS1
SCHEMBL26650892 0.78 CYP2C9 (0.45) LMNAGAAHSD17B10MAPT
SCHEMBL12785428 0.78 AHR (0.41) NOS3NOS1NOS2AHRCYP1A2
SCHEMBL28383627 0.78 MEN1 (0.49) AHRCYP1A2GAAHSD17B10MEN1
SCHEMBL23639908 0.76 NPC1 (0.41) CYP1A2ALOX5MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118405955-A Synthetic method of olefin compound 浙江工业大学 2024-07-30 CN disclosed