SCHEMBL30987564

SCHEMBL30987564

CNc1ccnc2c(NC(=O)N[C@@H]3C[C@@H]3F)cnn12

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TYK2 P29597 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30983197 0.82 TYK2 (0.58) TYK2
SCHEMBL23327549 0.77 TYK2 (0.60) TYK2
SCHEMBL23327175 0.76 TYK2 (0.55) TYK2
SCHEMBL30548446 0.75 TYK2 (0.66) TYK2
SCHEMBL23327450 0.75 TYK2 (0.66) TYK2
SCHEMBL23327690 0.75 TYK2 (0.58) TYK2
SCHEMBL23327511 0.74 TYK2 (0.51) TYK2
SCHEMBL23327712 0.74 TYK2 (0.51) TYK2
SCHEMBL23327181 0.72 TYK2 (0.57) TYK2
Cenacitinib SCHEMBL23327489 0.69 TYK2 (0.54) TYK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4649082-A1 PREPARATION OF A TYK2 INHIBITOR Ventyx Biosciences, Inc. (US) 2025-11-19 — — EP disclosed
WO-2024151992-A1 PREPARATION OF A TYK2 INHIBITOR VENTYX BIOSCIENCES, INC. (US) 2024-07-18 — — WO disclosed
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