SCHEMBL30988673

SCHEMBL30988673

Cc1cc(OC(F)F)c(O)c2ccn(C(=O)OC(C)(C)C)c12

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BUB1 O43683 1/20 0.36
PDE4D Q08499 1/20 0.35
ACLY P53396 1/20 0.33
BCHE P06276 1/20 0.33
HTR6 P50406 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31729934 0.86 BUB1 (0.37) BUB1ACLYBCHEHTR6L3MBTL1
SCHEMBL31729948 0.85 BUB1 (0.38) BUB1PDE4DACLYBCHEHTR6
SCHEMBL31317119 0.85 PDE4D (0.33) BUB1PDE4DACLYBCHE
SCHEMBL15366200 0.85 PDE4D (0.33) BUB1PDE4DACLYBCHE
SCHEMBL31317212 0.84 PDE4D (0.33) BUB1PDE4DACLYBCHEHSP90AA1
SCHEMBL18683189 0.84 PDE4D (0.33) BUB1PDE4DACLYBCHE
SCHEMBL15366333 0.84 PDE4D (0.33) BUB1PDE4DACLYBCHE
SCHEMBL15366332 0.84 PDE4D (0.33) BUB1PDE4DACLYBCHE
SCHEMBL31729933 0.83 BUB1 (0.37) BUB1PDE4DACLYBCHEHTR6
SCHEMBL31549571 0.82 BUB1 (0.44) BUB1ACLYBCHEHTR6L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4650351-A1 INHIBITOR OF COMPLEMENT FACTOR B Nanjing Chia Tai Tianqing Pharmaceutical Co., Ltd. (CN) 2025-11-19 EP disclosed
WO-2024149261-A1 INHIBITOR OF COMPLEMENT FACTOR B 南京正大天晴制药有限公司 2024-07-18 WO disclosed