Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 12/20 | 0.60 |
| ▸ | EGFR | P00533 | 7/20 | 0.57 |
| ▸ | KDR | P35968 | 6/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282184 | 0.86 | SRC (0.66) | SRCEGFRKDRERBB2 | |
| SCHEMBL30988726 | 0.82 | ERBB2 (0.53) | SRCEGFRKDRERBB2 | |
| SCHEMBL3204452 | 0.78 | SRC (0.84) | SRCEGFRKDRERBB2 | |
| SCHEMBL30227057 | 0.77 | SRC (0.60) | SRCEGFRKDR | |
| SCHEMBL5406753 | 0.77 | EGFR (0.73) | SRCEGFRKDRERBB2KCNH2 | |
| SCHEMBL3275698 | 0.77 | SRC (0.51) | SRCEGFRKDR | |
| SCHEMBL3194243 | 0.76 | SRC (0.81) | SRCEGFRKDRERBB2 | |
| SCHEMBL30988727 | 0.76 | SRC (0.58) | SRCEGFRKDRERBB2KCNH2 | |
| Hydrochloric Acid SCHEMBL3275787 | 0.76 | SRC (0.74) | SRCEGFRKDRERBB2 | |
| SCHEMBL4034788 | 0.76 | SRC (0.61) | SRCEGFRKDRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255772-A | Quinazoline derivatives as antitumor agents | 苏州赞荣医药科技有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118255772-A | Quinazoline derivatives as antitumor agents | 苏州赞荣医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |