Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 16/20 | 0.53 |
| ▸ | EGFR | P00533 | 9/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30988724 | 0.94 | ERBB2 (0.48) | ERBB2EGFRSRCPIK3CDPIK3CA | |
| SCHEMBL30988743 | 0.93 | ERBB2 (0.47) | ERBB2EGFRSRCPIK3CDPIK3CA | |
| SCHEMBL30988699 | 0.92 | ERBB2 (0.46) | ERBB2EGFRSRCPIK3CDPIK3CA | |
| SCHEMBL30988698 | 0.90 | ERBB2 (0.45) | ERBB2EGFRSRCPIK3CDPIK3CA | |
| SCHEMBL30658969 | 0.90 | ERBB2 (0.45) | ERBB2EGFRSRC | |
| SCHEMBL30988729 | 0.90 | ERBB2 (0.45) | ERBB2EGFRSRCPIK3CDPIK3CA | |
| SCHEMBL30988777 | 0.89 | ERBB2 (0.43) | ERBB2EGFR | |
| SCHEMBL30658932 | 0.89 | ERBB2 (0.43) | ERBB2EGFRSRCPIK3CDPIK3CA | |
| SCHEMBL30988706 | 0.89 | ERBB2 (0.44) | ERBB2EGFRSRCPIK3CDPIK3CA | |
| SCHEMBL30988746 | 0.88 | ERBB2 (0.42) | ERBB2EGFRSRCPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255772-A | Quinazoline derivatives as antitumor agents | 苏州赞荣医药科技有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118255772-A | Quinazoline derivatives as antitumor agents | 苏州赞荣医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |