Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30988928 | 1.00 | KCNH2 (0.58) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL19544879 | 1.00 | KCNH2 (0.58) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL5542817 | 0.90 | KCNH2 (0.57) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL16624944 | 0.88 | KCNH2 (0.59) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL30988920 | 0.87 | KCNH2 (0.60) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL5545216 | 0.86 | KCNH2 (0.58) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL14562959 | 0.86 | KCNH2 (0.58) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL1229290 | 0.86 | KCNH2 (0.58) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL5544271 | 0.84 | KCNH2 (0.56) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL14004055 | 0.83 | KCNH2 (0.55) | KCNH2CACNA1CSCN5APTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344384-A | Compounds and uses thereof | 丹诺医药(苏州）有限公司 | 2024-07-16 | — | — | CN | disclosed |