Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.46 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18013426 | 0.78 | USP30 (0.45) | BACE1BACE2USP30AAK1PRMT5 | |
| SCHEMBL30990275 | 0.78 | USP30 (0.47) | BACE1BACE2USP30AAK1PRMT5 | |
| SCHEMBL30990260 | 0.77 | BACE1 (0.32) | BACE1BACE2AAK1 | |
| SCHEMBL28555895 | 0.76 | BACE1 (0.42) | BACE1BACE2USP30AAK1 | |
| SCHEMBL29678448 | 0.75 | USP30 (0.47) | BACE1BACE2USP30AAK1PRMT5 | |
| SCHEMBL30990285 | 0.75 | CACNA1B (0.39) | BACE1BACE2 | |
| SCHEMBL31489757 | 0.74 | BACE1 (0.41) | BACE1BACE2USP30 | |
| SCHEMBL14786546 | 0.74 | BACE1 (0.46) | BACE1BACE2USP30AAK1PRMT5 | |
| SCHEMBL20508349 | 0.74 | USP30 (0.46) | BACE1BACE2USP30AAK1PRMT5 | |
| SCHEMBL22789710 | 0.73 | USP30 (0.45) | BACE1BACE2USP30AAK1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626860-A1 | FUSED PYRROLYL-SULFONAMIDE COMPOUNDS | ReWind Therapeutics NV (BE) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024115733-A1 | FUSED PYRROLYL-SULFONAMIDE COMPOUNDS | REWIND THERAPEUTICS NV (BE) | 2024-06-06 | — | — | WO | disclosed |