SCHEMBL30990293

SCHEMBL30990293

O=CCc1cc(F)c(Br)cc1F

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 6/20 0.36
KDM1B Q8NB78 4/20 0.36
KCNH2 Q12809 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12489957 1.00 KDM1A (0.36) KDM1AKDM1BKCNH2
SCHEMBL1421365 0.92
SCHEMBL486530 0.85
SCHEMBL2012031 0.84 ERN1 (0.33) KDM1AKDM1BKCNH2
SCHEMBL15067721 0.82 KDM1A (0.33) KDM1AKDM1BKCNH2
SCHEMBL2556351 0.82 DPP4 (0.38)
SCHEMBL30096747 0.82 DPP4 (0.38)
SCHEMBL1823434 0.82 PTPN1 (0.37)
SCHEMBL23064180 0.79 KDM1A (0.35) KDM1AKDM1B
SCHEMBL3828243 0.78 HTR2A (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626860-A1 FUSED PYRROLYL-SULFONAMIDE COMPOUNDS ReWind Therapeutics NV (BE) 2025-10-08 EP disclosed
WO-2024115733-A1 FUSED PYRROLYL-SULFONAMIDE COMPOUNDS REWIND THERAPEUTICS NV (BE) 2024-06-06 WO disclosed