⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9933980 | 1.00 | — | — | |
| SCHEMBL9933977 | 1.00 | — | — | |
| SCHEMBL19971668 | 1.00 | — | — | |
| SCHEMBL18764980 | 0.82 | — | — | |
| SCHEMBL20532799 | 0.82 | — | — | |
| SCHEMBL18765020 | 0.82 | — | — | |
| SCHEMBL20585977 | 0.80 | POLB (0.36) | — | |
| SCHEMBL20585975 | 0.80 | POLB (0.36) | — | |
| SCHEMBL3106502 | 0.80 | POLB (0.36) | — | |
| SCHEMBL18036560 | 0.80 | POLB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365339-A1 | NOVEL FERROPORTIN INHIBITORS | Vifor (International) AG (CH) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017068090-A1 | NOVEL FERROPORTIN INHIBITORS | VIFOR (INTERNATIONAL) AG (CH) | 2017-04-27 | — | — | WO | disclosed |
| US-8895602-B1 | 6-pyrazolylamido-3-substituted azabicyclo[3.1.0]hexane compounds as calcium channel inhibitors | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-11-25 | — | — | US | disclosed |
| US-20140343295-A1 | NOVEL 6-PYRAZOLYLAMIDO-3-SUBSTITUTED AZABICYCLO[3.1.0]HEXANE COMPOUNDS AS CALCIUM CHANNEL INHIBITORS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-11-20 | — | — | US | disclosed |
| US-20100256192-A1 | 3.1.0 BICYCLIC GLYT1 INHIBITORS AND METHODS OF MAKING AND USING SAME | VANDERBILT UNIVERSITY | 2010-10-07 | — | — | US | disclosed |