Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 20/20 | 0.65 |
| ▸ | BRD4 | O60885 | 4/20 | 0.50 |
| ▸ | EP300 | Q09472 | 3/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.49 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.49 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30992930 | 0.94 | CREBBP (0.75) | CREBBPBRD4EP300TRIM24BRD3 | |
| Lithium Ion SCHEMBL30992897 | 0.85 | CREBBP (0.75) | CREBBPBRD4EP300TRIM24BRD3 | |
| SCHEMBL30993056 | 0.80 | CREBBP (0.69) | CREBBPBRD4EP300 | |
| SCHEMBL29704371 | 0.79 | CREBBP (1.00) | CREBBPBRD4EP300TRIM24BRD3 | |
| SCHEMBL19643793 | 0.79 | CREBBP (1.00) | CREBBPBRD4EP300TRIM24BRD3 | |
| SCHEMBL30993681 | 0.77 | CREBBP (0.49) | CREBBPBRD4EP300TRIM24BRD3 | |
| SCHEMBL19657696 | 0.76 | CREBBP (0.84) | CREBBPBRD4EP300TRIM24BRD3 | |
| SCHEMBL30992909 | 0.76 | CREBBP (0.69) | CREBBPBRD4EP300 | |
| SCHEMBL31248640 | 0.75 | CREBBP (0.72) | CREBBPBRD4EP300 | |
| SCHEMBL30993020 | 0.74 | CREBBP (0.69) | CREBBPBRD4EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |