Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13778074 | 0.84 | KDM4E (0.55) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL17732301 | 0.84 | KDM4E (0.65) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL24395078 | 0.83 | KDM4E (0.54) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL19436634 | 0.81 | KDM4E (0.53) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL19436637 | 0.81 | KDM4E (0.50) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL20689018 | 0.81 | KDM4E (0.52) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL25070256 | 0.80 | KDM4E (0.51) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL31245710 | 0.78 | KDM4E (0.49) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL20697186 | 0.77 | KDM4E (0.53) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL10407266 | 0.76 | KDM4E (0.55) | KDM4EHSD17B10HPGDALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |