Salicylamide

Salicylamide

SCHEMBL30995449

N.NC(=O)c1ccccc1O

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.95
HPGD P15428 5/20 0.95
ALDH1A1 P00352 4/20 0.95
HSD17B10 Q99714 3/20 0.95
TSHR P16473 2/20 0.95
MAPT P10636 1/20 0.95
CA1 P00915 2/20 0.58
CA9 Q16790 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
CA12 O43570 1/20 0.58
CA2 P00918 1/20 0.58
HMGB1 P09429 1/20 0.58
CA4 P22748 1/20 0.58
CA6 P23280 1/20 0.58
CA7 P43166 1/20 0.58
NAPRT Q6XQN6 1/20 0.58
CA14 Q9ULX7 1/20 0.58
GAA P10253 3/20 0.52
MPO P05164 1/20 0.52
HIF1A Q16665 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylamide SCHEMBL27977401 1.00 KDM4E (0.95) KDM4EHPGDALDH1A1HSD17B10TSHR
Salicylamide SCHEMBL29384763 0.97 KDM4E (1.00) KDM4EHPGDALDH1A1HSD17B10TSHR
Salicylamide SCHEMBL21646 0.97 KDM4E (1.00) KDM4EHPGDALDH1A1HSD17B10TSHR
Salicylamide SCHEMBL27497234 0.97 KDM4E (1.00) KDM4EHPGDALDH1A1HSD17B10TSHR
Salicylamide SCHEMBL723112 0.95 KDM4E (0.95) KDM4EHPGDALDH1A1HSD17B10TSHR
Salicylamide SCHEMBL4949313 0.95 KDM4E (0.95) KDM4EHPGDALDH1A1HSD17B10TSHR
Salicylamide SCHEMBL473700 0.95 KDM4E (0.95) KDM4EHPGDALDH1A1HSD17B10TSHR
Salicylamide SCHEMBL7198790 0.95 KDM4E (0.95) KDM4EHPGDALDH1A1HSD17B10TSHR
Salicylamide SCHEMBL11412975 0.95 KDM4E (0.95) KDM4EHPGDALDH1A1HSD17B10TSHR
Salicylamide SCHEMBL18729462 0.95 KDM4E (0.95) KDM4EHPGDALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634169-A1 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF Pfizer Inc. (US) 2025-10-22 EP disclosed
WO-2024127297-A1 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF PFIZER INC. (US) 2024-06-20 WO disclosed