Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959957 | 1.00 | TMPRSS2 (0.43) | TMPRSS2TRPA1CTSKCTSSCTSL | |
| SCHEMBL24916976 | 0.94 | TMPRSS2 (0.39) | TMPRSS2TRPA1CTSKCTSSCTSL | |
| SCHEMBL25924504 | 0.92 | TMPRSS2 (0.44) | TMPRSS2CSNK2A2CSNK2A1EGLN2RIPK1 | |
| SCHEMBL24917354 | 0.92 | TMPRSS2 (0.44) | TMPRSS2CSNK2A2CSNK2A1EGLN2RIPK1 | |
| SCHEMBL24917150 | 0.92 | TMPRSS2 (0.37) | TMPRSS2TRPA1CTSKCTSSCSNK2A2 | |
| SCHEMBL25915804 | 0.91 | TMPRSS2 (0.37) | TMPRSS2TRPA1CTSKCTSS | |
| SCHEMBL24916981 | 0.91 | TMPRSS2 (0.37) | TMPRSS2TRPA1CTSKCTSS | |
| SCHEMBL24917224 | 0.90 | TMPRSS2 (0.36) | TMPRSS2TRPA1 | |
| SCHEMBL24916973 | 0.89 | TMPRSS2 (0.36) | TMPRSS2TRPA1 | |
| SCHEMBL24916958 | 0.89 | TMPRSS2 (0.37) | TMPRSS2TRPA1CTSKCTSSCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204421-B1 | COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS | GILEAD SCIENCES INC (US) | 2024-05-15 | — | — | EP | disclosed |