Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 10/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31421648 | 1.00 | MC4R (0.53) | MC4RKCNH2HDAC4HDAC6IDH1 | |
| SCHEMBL31421655 | 0.90 | MC4R (0.64) | MC4RKCNH2HDAC4HDAC6IDH1 | |
| SCHEMBL30996531 | 0.90 | MC4R (0.64) | MC4RKCNH2HDAC4HDAC6IDH1 | |
| SCHEMBL25437281 | 0.88 | MC4R (0.55) | MC4RKCNH2BTKMAPT | |
| SCHEMBL31421667 | 0.88 | MC4R (0.63) | MC4RKCNH2HDAC4HDAC6IDH1 | |
| SCHEMBL31421691 | 0.82 | MC4R (0.48) | MC4RKCNH2HDAC4HDAC6IDH1 | |
| SCHEMBL31421659 | 0.81 | MC4R (0.63) | MC4RKCNH2HDAC4HDAC6IDH1 | |
| SCHEMBL31421671 | 0.81 | MC4R (0.69) | MC4RKCNH2HDAC4HDAC6IDH1 | |
| SCHEMBL30458036 | 0.81 | MC4R (0.57) | MC4RKCNH2IDH1BTKUSP30 | |
| SCHEMBL30833316 | 0.81 | MC4R (0.57) | MC4RKCNH2IDH1BTKUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118369317-A | Melanocortin 4 receptor antagonists and uses thereof | 辉瑞大药厂 | 2024-07-19 | — | — | CN | disclosed |