SCHEMBL30998136

SCHEMBL30998136

CCCCCCCCOc1ccc2sc3ccccc3c(=O)c2c1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.62
NPC1 O15118 1/20 0.62
ALDH1A1 P00352 1/20 0.62
MAPT P10636 1/20 0.62
RAB9A P51151 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
MAOA P21397 9/20 0.47
MAOB P27338 9/20 0.47
PTPN11 Q06124 1/20 0.44
ACSL1 P33121 1/20 0.44
ACSL6 Q9UKU0 1/20 0.44
TSHR P16473 1/20 0.43
LTA4H P09960 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20594371 1.00 KDM4E (0.62) KDM4ENPC1ALDH1A1MAPTRAB9A
SCHEMBL20594289 1.00 KDM4E (0.62) KDM4ENPC1ALDH1A1MAPTRAB9A
SCHEMBL20594294 1.00 KDM4E (0.62) KDM4ENPC1ALDH1A1MAPTRAB9A
SCHEMBL30998126 1.00 KDM4E (0.62) KDM4ENPC1ALDH1A1MAPTRAB9A
SCHEMBL30998120 1.00 KDM4E (0.62) KDM4ENPC1ALDH1A1MAPTRAB9A
SCHEMBL20594287 1.00 KDM4E (0.62) KDM4ENPC1ALDH1A1MAPTRAB9A
SCHEMBL13338859 0.92 KDM4E (0.51) KDM4ENPC1ALDH1A1MAPTRAB9A
SCHEMBL1505814 0.91 MAPT (0.67) KDM4ENPC1ALDH1A1MAPTRAB9A
SCHEMBL13338844 0.88 KDM4E (0.55) KDM4ENPC1ALDH1A1MAPTRAB9A
SCHEMBL25998635 0.85 KDM4E (0.68) KDM4ENPC1ALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024153871-A1 ADDITIVE MANUFACTURING METHOD FOR PRODUCING A SILICONE ELASTOMER ARTICLE ELKEM SILICONES FRANCE SAS (FR) 2024-07-25 WO disclosed