SCHEMBL31000258

SCHEMBL31000258

CC(O)(c1ccc(N)nc1)C(F)(F)F

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCKR Q14397 20/20 0.68
GCK P35557 17/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18053746 1.00 GCKR (0.68) GCKRGCK
SCHEMBL15202906 0.82 GCK (1.00) GCKRGCK
SCHEMBL15200848 0.82 GCK (1.00) GCKRGCK
SCHEMBL15200996 0.82 GCK (1.00) GCKRGCK
SCHEMBL15202910 0.82 GCKR (0.67) GCKRGCK
SCHEMBL16799601 0.81 GCK (0.59) GCKRGCK
SCHEMBL21848291 0.81 GCKR (0.49) GCKRGCK
SCHEMBL1725656 0.80 GCK (0.47) GCKRGCK
SCHEMBL30256450 0.80 GCK (0.47) GCKRGCK
SCHEMBL29127263 0.80 GCK (0.47) GCKRGCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658659-A2 MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF Children's Hospital Medical Center (US) 2025-12-10 EP disclosed
WO-2024163764-A2 MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2024-08-08 WO disclosed