Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398713 | 1.00 | TLR2 (0.53) | TLR2KMT2AHDAC1HDAC2MDM4 | |
| SCHEMBL12221104 | 1.00 | TLR2 (0.53) | TLR2KMT2AHDAC1HDAC2MDM4 | |
| SCHEMBL12221123 | 1.00 | TLR2 (0.53) | TLR2KMT2AHDAC1HDAC2MDM4 | |
| Hydrochloric Acid SCHEMBL29217894 | 0.99 | TLR2 (0.54) | TLR2KMT2AHDAC1HDAC2MDM4 | |
| Hydrochloric Acid SCHEMBL30202339 | 0.99 | TLR2 (0.54) | TLR2KMT2AHDAC1HDAC2MDM4 | |
| Hydrochloric Acid SCHEMBL25358748 | 0.99 | TLR2 (0.54) | TLR2KMT2AHDAC1HDAC2MDM4 | |
| Hydrochloric Acid SCHEMBL30003033 | 0.99 | TLR2 (0.54) | TLR2KMT2AHDAC1HDAC2MDM4 | |
| Hydrochloric Acid SCHEMBL25358745 | 0.99 | TLR2 (0.54) | TLR2KMT2AHDAC1HDAC2MDM4 | |
| Hydrochloric Acid SCHEMBL29401186 | 0.99 | TLR2 (0.54) | TLR2KMT2AHDAC1HDAC2MDM4 | |
| SCHEMBL30819043 | 0.97 | TLR2 (0.50) | TLR2KMT2AHDAC1HDAC2MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151843-A1 | TARGETED UNIVERSAL DELIVERY SYSTEM OF DON AND OTHER DRUGS | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-07-18 | — | — | WO | disclosed |