Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.48 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 2/20 | 0.46 |
| ▸ | SKP1 | P63208 | 2/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25189993 | 1.00 | MAP4K4 (0.49) | MAP4K4SMARCA2SMARCA4PBRM1ADORA2A | |
| SCHEMBL16427591 | 0.88 | POLB (0.46) | MAP4K4SMARCA2SMARCA4PBRM1CKS1B | |
| SCHEMBL30419540 | 0.88 | POLB (0.46) | MAP4K4SMARCA2SMARCA4PBRM1CKS1B | |
| SCHEMBL20919447 | 0.85 | BACE1 (0.46) | MAP4K4SMARCA2SMARCA4PBRM1CKS1B | |
| SCHEMBL30418929 | 0.85 | MAP4K4 (0.51) | MAP4K4SMARCA2SMARCA4PBRM1ADORA2A | |
| SCHEMBL21698657 | 0.85 | MAP4K4 (0.51) | MAP4K4SMARCA2SMARCA4PBRM1ADORA2A | |
| SCHEMBL30720173 | 0.84 | CKS1B (0.47) | MAP4K4SMARCA2SMARCA4PBRM1CKS1B | |
| SCHEMBL27260592 | 0.84 | CKS1B (0.47) | MAP4K4SMARCA2SMARCA4PBRM1CKS1B | |
| SCHEMBL31006176 | 0.84 | MAP4K4 (0.50) | MAP4K4SMARCA2SMARCA4PBRM1ADORA2A | |
| SCHEMBL25314946 | 0.84 | MAP4K4 (0.50) | MAP4K4SMARCA2SMARCA4PBRM1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118871445-A | Fused triazinone derivatives and methods of use thereof | 亚根达医疗公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118475571-A | Degradation of Bruton Tyrosine Kinase (BTK) by conjugation of BTK inhibitors to E3 ligase ligands and methods of use | 百济神州有限公司 | 2024-08-09 | — | — | CN | disclosed |