⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12493612 | 0.85 | — | — | |
| Biphenyl SCHEMBL11504602 | 0.77 | PDCD1 (0.46) | — | |
| SCHEMBL7417411 | 0.72 | — | — | |
| SCHEMBL3620607 | 0.69 | — | — | |
| SCHEMBL1149313 | 0.67 | — | — | |
| SCHEMBL15388940 | 0.67 | — | — | |
| SCHEMBL15876806 | 0.67 | — | — | |
| SCHEMBL1149385 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL6843030 | 0.64 | — | — | |
| SCHEMBL7357720 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772751-A | EASILY SEPARATED FROM BY-PRODUCTS | ALDRICH-BORANES, INC. (US) | 1988-09-20 | — | — | US | claimed |
| US-12091425-B2 | Compounds that inhibit MCL-1 protein | AMGEN INC. (US) | 2024-09-17 | — | — | US | disclosed |
| US-11760728-B2 | Tead inhibitors and uses thereof | Ikena Oncology, Inc. (US) | 2023-09-19 | — | — | US | disclosed |
| WO-2023127495-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT | キヤノン株式会社 | 2023-07-06 | — | — | WO | disclosed |
| US-20230052348-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2023-02-16 | — | — | US | disclosed |
| US-11306107-B2 | Compounds that inhibit MCL-1 protein | AMGEN INC. (US) | 2022-04-19 | — | — | US | disclosed |
| CN-107188898-B | Process for preparing thienopyrimidine compounds | 霍夫曼-拉罗奇有限公司 | 2019-12-03 | — | — | CN | disclosed |
| CN-106573934-B | The inhibition of transient receptor potential A1 ion channel | 伊莱利利公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-109890385-A | Crystalline forms of (1R,2R) -2- [4- (3-methyl-1H-pyrazol-5-yl) benzoyl ] -N- (4-oxo-4, 5,6, 7-tetrahydropyrazolo [1,5-a ] pyrazin-3-yl) cyclohexanecarboxamide | 阿斯利康(瑞典)有限公司 | 2019-06-14 | — | — | CN | disclosed |
| EP-2892904-B1 | HIGHLY SELECTIVE C-MET INHIBITORS AS ANTICANCER AGENTS | CB THERAPEUTICS INC (KY) | 2018-10-17 | — | — | EP | disclosed |
| US-20150218171-A1 | HIGHLY SELECTIVE C-MET INHIBITORS AS ANTICANCER AGENTS | APOLLOMICS INC. | 2015-08-06 | — | — | US | disclosed |
| EP-2892904-A1 | HIGHLY SELECTIVE C-MET INHIBITORS AS ANTICANCER AGENTS | Crown Bioscience Inc. (Taiwan) (CN) | 2015-07-15 | — | — | EP | disclosed |
| US-8957407-B2 | Anthracene derivatives, preparation method thereof and organic light emitting diode using the same | LG CHEM, LTD. (KR) | 2015-02-17 | — | — | US | disclosed |
| WO-2014032498-A1 | HIGHLY SELECTIVE C-MET INHIBITORS AS ANTICANCER AGENTS | CROWN BIOSCIENCE INC. (TAICANG) (CN) | 2014-03-06 | — | — | WO | disclosed |
| US-20130178575-A1 | CYCLIC OLEFIN COPOLYMER AND CROSSLINKED POLYMER THEREOF | MITSUI CHEMICALS, INC. (JP) | 2013-07-11 | — | — | US | disclosed |
| WO-2012154849-A1 | POLYMER COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2012-11-15 | — | — | WO | disclosed |
| US-20100252817-A1 | New Anthracene Derivatives, Preparation Method Thereof and Organic Light Emitting Diode Using the Same | LG CHEM. LTD. (KR) | 2010-10-07 | — | — | US | disclosed |
| EP-1976814-A1 | NEW ANTHRACENE DERIVATIVES, PREPARATION METHOD THEREOF AND ORGANIC LIGHT EMITTING DIODE USING THE SAME | LG Chem, Ltd. (KR) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007086695-A1 | NEW ANTHRACENE DERIVATIVES, PREPARATION METHOD THEREOF AND ORGANIC LIGHT EMITTING DIODE USING THE SAME | LG CHEM. LTD. (KR) | 2007-08-02 | — | — | WO | disclosed |
| WO-2006065001-A1 | BIMETALLIC ZINC COMPLEX AND PROCESS OF PRODUCING POLYCARBONATE USING THE SAME AS POLYMERIZATION CATALYST | LG CHEM. LTD. (KR) | 2006-06-22 | — | — | WO | disclosed |