Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DHPS | P49366 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283820 | 1.00 | ADORA2A (0.55) | ADORA2AALDH1A1CFTRHSP90AB1HDAC8 | |
| SCHEMBL31006532 | 0.91 | HSP90AB1 (0.50) | ADORA2AALDH1A1HSP90AB1HDAC8ROCK2 | |
| SCHEMBL29283805 | 0.91 | HSP90AB1 (0.50) | ADORA2AALDH1A1HSP90AB1HDAC8ROCK2 | |
| SCHEMBL31006546 | 0.89 | HSP90AB1 (0.63) | ADORA2AALDH1A1CFTRHSP90AB1HDAC8 | |
| SCHEMBL29283858 | 0.89 | HSP90AB1 (0.63) | ADORA2AALDH1A1CFTRHSP90AB1HDAC8 | |
| SCHEMBL31006516 | 0.86 | HSP90AB1 (0.57) | ADORA2AALDH1A1HSP90AB1ROCK2ROCK1 | |
| SCHEMBL29283795 | 0.86 | HSP90AB1 (0.57) | ADORA2AALDH1A1HSP90AB1ROCK2ROCK1 | |
| SCHEMBL31006554 | 0.84 | POLB (0.42) | ADORA2AALDH1A1CFTRHSP90AB1HDAC8 | |
| SCHEMBL29283872 | 0.84 | POLB (0.42) | ADORA2AALDH1A1CFTRHSP90AB1HDAC8 | |
| SCHEMBL31006556 | 0.82 | HSP90AB1 (0.51) | ALDH1A1HSP90AB1ROCK2ROCK1DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |