Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.49 |
| ▸ | CCNK | O75909 | 9/20 | 0.48 |
| ▸ | CDK12 | Q9NYV4 | 9/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.48 |
| ▸ | CDK2 | P24941 | 8/20 | 0.48 |
| ▸ | CDK9 | P50750 | 8/20 | 0.48 |
| ▸ | CDK7 | P50613 | 4/20 | 0.48 |
| ▸ | CCNH | P51946 | 4/20 | 0.48 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17961774 | 0.79 | KDM4E (0.46) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL17961772 | 0.79 | KDM4E (0.46) | CCNKCDK12CCNT1CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL23295751 | 0.78 | CHEK1 (0.45) | CCNKCDK12CCNT1CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL28546461 | 0.78 | CHEK1 (0.45) | CCNKCDK12CCNT1CCNE1CDK2 | |
| Trifluoroacetic Acid SCHEMBL28555886 | 0.78 | HRH4 (0.51) | CCNKCDK12CCNT1CCNE1CDK2 | |
| Trifluoroacetic Acid SCHEMBL28555887 | 0.78 | HRH4 (0.51) | CCNKCDK12CCNT1CCNE1CDK2 | |
| Trifluoroacetic Acid SCHEMBL28549613 | 0.78 | HRH4 (0.51) | IRAK4CCNKCDK12CCNT1CCNE1 | |
| Trifluoroacetic Acid SCHEMBL28549612 | 0.78 | HRH4 (0.51) | IRAK4CCNKCDK12CCNT1CCNE1 | |
| Trifluoroacetic Acid SCHEMBL28549784 | 0.76 | HRH4 (0.59) | IRAK4CDK2CHEK1 | |
| Trifluoroacetic Acid SCHEMBL28549783 | 0.76 | HRH4 (0.59) | IRAK4CDK2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480029-A | 2-Aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-08-13 | — | — | CN | disclosed |