Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 16/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 16/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31006819 | 1.00 | MTOR (0.49) | MTORPIK3R1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL31006771 | 0.85 | MTOR (0.41) | MTORRAF1BRAF | |
| SCHEMBL31006848 | 0.81 | MTOR (0.47) | MTORPIK3R1PIK3CARAF1BRAF | |
| SCHEMBL24074637 | 0.80 | PIK3CA (0.50) | MTORPIK3R1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL30339414 | 0.80 | PIK3CA (0.50) | MTORPIK3R1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL31006857 | 0.80 | CYP8B1 (0.43) | MTORPIK3CD | |
| SCHEMBL441537 | 0.76 | MTOR (0.59) | MTORPIK3R1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL22718259 | 0.76 | MTOR (0.59) | MTORPIK3R1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL24955676 | 0.75 | MTOR (0.57) | MTORPIK3R1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL20042972 | 0.73 | MTOR (0.47) | MTORPIK3R1PIK3CAPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480029-A | 2-Aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-08-13 | — | — | CN | disclosed |