Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 16/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 13/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129949 | 1.00 | GRIN2B (0.57) | GRIN2BGRIN1MEN1LMNAPABPC1 | |
| SCHEMBL20129950 | 0.87 | GRIN1 (0.56) | GRIN2BGRIN1MEN1LMNAPABPC1 | |
| SCHEMBL30532178 | 0.82 | GRIN2B (0.44) | GRIN2BGRIN1LMNA | |
| SCHEMBL31008693 | 0.75 | GRIN1 (0.81) | GRIN2BGRIN1 | |
| SCHEMBL20129953 | 0.75 | GRIN1 (0.81) | GRIN2BGRIN1 | |
| SCHEMBL20129948 | 0.75 | MEN1 (0.54) | GRIN2BGRIN1MEN1LMNAPABPC1 | |
| SCHEMBL20129934 | 0.74 | MEN1 (0.59) | GRIN2BGRIN1MEN1LMNAPABPC1 | |
| SCHEMBL22771400 | 0.74 | GRIN2B (0.56) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL29525178 | 0.74 | GRIN2B (0.56) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL20130209 | 0.73 | GRIN1 (1.00) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989164-B | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2024-08-13 | — | — | CN | disclosed |