Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25420050 | 1.00 | HSD17B10 (0.41) | HSD17B10TRPC5TSHRKDM4EKDM4A | |
| SCHEMBL21836748 | 0.86 | APEX1 (0.43) | HSD17B10TSHRKDM4EKDM4AALDH1A1 | |
| SCHEMBL28736559 | 0.84 | GRIN1 (0.50) | HSD17B10GRIN1GRIN2B | |
| SCHEMBL20129937 | 0.84 | HSD17B10 (0.38) | HSD17B10TSHRKDM4EKDM4AALDH1A1 | |
| SCHEMBL31008729 | 0.84 | HSD17B10 (0.38) | HSD17B10TSHRKDM4EKDM4AALDH1A1 | |
| SCHEMBL25224076 | 0.82 | GRIN1 (0.50) | HSD17B10GRIN1GRIN2B | |
| SCHEMBL31008675 | 0.82 | GRIN1 (0.50) | HSD17B10GRIN1GRIN2B | |
| SCHEMBL25421015 | 0.82 | HSD17B10 (0.60) | HSD17B10TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL30381462 | 0.82 | HSD17B10 (0.60) | HSD17B10TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL29636067 | 0.81 | GRIN1 (0.51) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989164-B | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2024-08-13 | — | — | CN | disclosed |