SCHEMBL31011815

SCHEMBL31011815

CC(C)(C)OC(=O)N1CCC2(CC1)CC(CNc1ccc(S(=O)(=O)NC(=O)c3ccc(N4CCN([C@@H]5CCCCc6c(Cl)cccc65)CC4)cc3)cc1[N+](=O)[O-])C2

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 20/20 0.54
BCL2L1 Q07817 18/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31011920 0.93 BCL2L1 (0.51) BCL2BCL2L1
SCHEMBL29329738 0.93 BCL2L1 (0.51) BCL2BCL2L1
SCHEMBL31011867 0.91 BCL2 (0.46) BCL2BCL2L1
SCHEMBL29325514 0.91 BCL2 (0.46) BCL2BCL2L1
SCHEMBL31011905 0.91 BCL2 (0.47) BCL2BCL2L1
SCHEMBL29325521 0.91 BCL2 (0.47) BCL2BCL2L1
SCHEMBL31011826 0.89 BCL2L1 (0.48) BCL2BCL2L1
SCHEMBL29328755 0.89 BCL2L1 (0.48) BCL2BCL2L1
SCHEMBL31011849 0.88 BCL2 (0.47) BCL2BCL2L1
SCHEMBL29325518 0.88 BCL2 (0.47) BCL2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239792-A1 MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF ASIA VISION LIMITED (CN) 2024-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239792-A1 MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF BCL2, BCL2L2, BCL2L1 BCL2 1/4885BCL2L1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.