Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 3/20 | 0.35 |
| ▸ | MMP7 | P09237 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | MMP8 | P22894 | 3/20 | 0.35 |
| ▸ | MMP13 | P45452 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31012164 | 1.00 | CETP (0.41) | CETPCCR3GPR119GAATP53 | |
| SCHEMBL30360885 | 1.00 | CETP (0.41) | CETPCCR3GPR119GAATP53 | |
| SCHEMBL30360954 | 1.00 | CETP (0.41) | CETPCCR3GPR119GAATP53 | |
| SCHEMBL31012165 | 1.00 | CETP (0.41) | CETPCCR3GPR119GAATP53 | |
| SCHEMBL16620129 | 0.89 | PDE5A (0.38) | CETPCCR3GPR119TP53 | |
| SCHEMBL16629753 | 0.89 | PDE5A (0.38) | CETPCCR3GPR119TP53 | |
| SCHEMBL31012163 | 0.88 | CETP (0.40) | CETPCCR3TP53ALDH1A1LMNA | |
| SCHEMBL29273734 | 0.88 | CETP (0.40) | CETPCCR3TP53ALDH1A1LMNA | |
| SCHEMBL31012162 | 0.88 | CETP (0.40) | CETPCCR3TP53ALDH1A1LMNA | |
| SCHEMBL29273736 | 0.88 | CETP (0.40) | CETPCCR3TP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118215652-A | Substituted hydroxymethyl pyrrolidines and medical uses thereof | 阿托基公司 | 2024-06-18 | — | — | CN | disclosed |