Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 6/20 | 0.54 |
| ▸ | MDM4 | O15151 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34461958 | 1.00 | MDM2 (0.54) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL20876881 | 1.00 | MDM2 (0.54) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL34461960 | 1.00 | MDM2 (0.54) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL15942924 | 1.00 | MDM2 (0.54) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL2198517 | 0.99 | MDM2 (0.53) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL34461962 | 0.99 | MDM2 (0.53) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL20876827 | 0.99 | MDM2 (0.53) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL34461955 | 0.99 | MDM2 (0.53) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL31013147 | 0.99 | MDM2 (0.53) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL34461957 | 0.99 | MDM2 (0.53) | MDM2MDM4TP53TLR2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051332-B | Immunomodulators | 百时美施贵宝公司 | 2024-09-06 | — | — | CN | disclosed |