Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31014190 | 0.94 | MAOB (0.41) | MAOBIDO1MAOAABCG2BCHE | |
| SCHEMBL31014188 | 0.93 | ABCG2 (0.45) | MAOBIDO1MAOAABCG2ABCB1 | |
| SCHEMBL31014191 | 0.93 | MAOB (0.41) | MAOBIDO1MAOAABCG2ABCB1 | |
| SCHEMBL31014189 | 0.91 | IDO1 (0.42) | MAOBIDO1MAOAABCG2ABCB1 | |
| SCHEMBL31014208 | 0.88 | MAOB (0.39) | MAOBIDO1MAOAABCG2ALDH1A1 | |
| SCHEMBL31091516 | 0.86 | MAOB (0.54) | MAOBIDO1MAOAABCB1BCHE | |
| SCHEMBL31014193 | 0.81 | IDO1 (0.40) | MAOBIDO1MAOALMNA | |
| SCHEMBL31091523 | 0.78 | IDO1 (0.54) | MAOBIDO1MAOAALDH1A1LMNA | |
| SCHEMBL31091514 | 0.77 | MAOB (0.53) | MAOBIDO1MAOAALDH1A1 | |
| SCHEMBL31011134 | 0.76 | IDO1 (0.56) | MAOBIDO1MAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118440025-B | Zhu Gongjun acid derivative and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-118440025-A | Zhu Gongjun acid derivative and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |