Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.48 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.48 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31014284 | 0.94 | NPSR1 (0.67) | NPSR1ATMLMNATSHRROCK1 | |
| SCHEMBL16363708 | 0.84 | ATM (0.46) | NPSR1ATMLMNATSHRMAP2K4 | |
| SCHEMBL4837386 | 0.82 | ENPP1 (0.56) | LMNAROCK1MAPK1MAP2K4MAPKAPK3 | |
| SCHEMBL1786578 | 0.81 | ATM (0.73) | NPSR1ATMLMNATSHRROCK1 | |
| SCHEMBL24000807 | 0.81 | MAP2K4 (0.50) | NPSR1ATMLMNATSHRMAPK1 | |
| SCHEMBL29870198 | 0.81 | NPSR1 (1.00) | NPSR1ATMLMNATSHRROCK1 | |
| SCHEMBL581143 | 0.81 | NPSR1 (1.00) | NPSR1ATMLMNATSHRROCK1 | |
| SCHEMBL4843618 | 0.80 | GSK3A (0.65) | NPSR1ATMROCK1MAPK1PDE4A | |
| SCHEMBL31014283 | 0.78 | NPSR1 (0.68) | NPSR1ATMLMNATSHRROCK1 | |
| SCHEMBL4005413 | 0.78 | MAP2K4 (0.65) | MAPK1MAP2K4MAPKAPK3MAPK6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496166-A | Preparation method of phthalazinone compound | 五邑大学 | 2024-08-16 | — | — | CN | claimed |
| CN-118496166-A | Preparation method of phthalazinone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |