Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.57 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706420 | 1.00 | ATM (0.73) | ATMNPSR1KDM4EALDH1A1POLB | |
| SCHEMBL29870198 | 0.85 | NPSR1 (1.00) | ATMNPSR1KDM4EALDH1A1POLB | |
| SCHEMBL581143 | 0.85 | NPSR1 (1.00) | ATMNPSR1KDM4EALDH1A1POLB | |
| SCHEMBL1932753 | 0.85 | NPSR1 (0.54) | ATMNPSR1KDM4EALDH1A1POLB | |
| SCHEMBL1791310 | 0.82 | ATM (0.73) | ATMNPSR1KDM4EALDH1A1POLB | |
| SCHEMBL31014290 | 0.82 | ATM (0.73) | ATMNPSR1KDM4EALDH1A1POLB | |
| SCHEMBL29710440 | 0.82 | ATM (0.73) | ATMNPSR1KDM4EALDH1A1POLB | |
| SCHEMBL3710852 | 0.82 | ATM (0.73) | ATMNPSR1KDM4EALDH1A1POLB | |
| SCHEMBL1904310 | 0.82 | ATM (0.73) | ATMNPSR1KDM4EALDH1A1POLB | |
| SCHEMBL29363334 | 0.82 | ATM (0.73) | ATMNPSR1KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496166-A | Preparation method of phthalazinone compound | 五邑大学 | 2024-08-16 | — | — | CN | claimed |
| CN-118496166-A | Preparation method of phthalazinone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |