Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 19/20 | 1.00 |
| ▸ | EHMT2 | Q96KQ7 | 12/20 | 1.00 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.82 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.82 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31016460 | 0.91 | NSD2 (1.00) | NSD2EHMT2PRMT1EHMT1 | |
| SCHEMBL25226192 | 0.90 | NSD2 (1.00) | NSD2EHMT2PRMT1EHMT1CARM1 | |
| SCHEMBL25198563 | 0.88 | NSD2 (0.81) | NSD2EHMT2PRMT1EHMT1CARM1 | |
| SCHEMBL31016436 | 0.87 | EHMT2 (0.77) | NSD2EHMT2PRMT1EHMT1 | |
| SCHEMBL21178846 | 0.86 | EHMT2 (0.76) | NSD2EHMT2PRMT1EHMT1 | |
| SCHEMBL25266375 | 0.85 | NSD2 (0.79) | NSD2EHMT2PRMT1EHMT1CARM1 | |
| SCHEMBL19462237 | 0.85 | EHMT2 (0.82) | NSD2EHMT2EHMT1 | |
| SCHEMBL25202661 | 0.85 | NSD2 (0.78) | NSD2EHMT2PRMT1EHMT1CARM1 | |
| SCHEMBL31016450 | 0.83 | NSD2 (1.00) | NSD2EHMT2PRMT1EHMT1CARM1 | |
| SCHEMBL21178812 | 0.81 | EHMT2 (0.85) | NSD2EHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373805-A | NSD2 small molecule inhibitor and preparation method and application thereof | 中山大学 | 2024-07-23 | — | — | CN | disclosed |