SCHEMBL31017705

SCHEMBL31017705

O=S(=O)(Nc1cscn1)c1ccc(NCc2c(F)cccc2CN2C3CCC2CC3)c(C(F)(F)F)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 20/20 1.00
SCN1A P35498 16/20 1.00
SCN5A Q14524 13/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21783419 1.00 SCN8A (1.00) SCN8ASCN1ASCN5A
Trifluoroacetic Acid SCHEMBL30045956 0.96 SCN8A (0.92) SCN8ASCN1ASCN5A
Trifluoroacetic Acid SCHEMBL21955469 0.96 SCN8A (0.92) SCN8ASCN1ASCN5A
SCHEMBL31017726 0.89 SCN8A (1.00) SCN8ASCN1ASCN5A
SCHEMBL21955478 0.89 SCN8A (1.00) SCN8ASCN1ASCN5A
SCHEMBL21783436 0.89 SCN8A (1.00) SCN8ASCN1ASCN5A
Trifluoroacetic Acid SCHEMBL30046603 0.87 SCN8A (0.89) SCN8ASCN1ASCN5A
Trifluoroacetic Acid SCHEMBL21955497 0.87 SCN8A (0.89) SCN8ASCN1ASCN5A
SCHEMBL22005599 0.84 SCN8A (0.73) SCN8ASCN1ASCN5A
SCHEMBL22331189 0.83 SCN8A (1.00) SCN8ASCN1ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638879-B Heteroaryl substituted sulfonamide compounds and their use as therapeutic agents 泽农医药公司 2024-06-18 CN claimed
CN-112638879-B Heteroaryl substituted sulfonamide compounds and their use as therapeutic agents 泽农医药公司 2024-06-18 CN disclosed