SCHEMBL31017709

SCHEMBL31017709

Cc1nc(S(=O)(=O)Nc2cscn2)c(F)cc1NCc1cccc(C(F)(F)F)c1CN1C2CCC1CC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 20/20 1.00
SCN1A P35498 16/20 1.00
SCN5A Q14524 12/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21955475 1.00 SCN8A (1.00) SCN8ASCN1ASCN5A
SCHEMBL31017723 0.89 SCN8A (1.00) SCN8ASCN1ASCN5A
SCHEMBL21955514 0.89 SCN8A (1.00) SCN8ASCN1ASCN5A
SCHEMBL21783405 0.89 SCN8A (1.00) SCN8ASCN1ASCN5A
SCHEMBL22005593 0.80 SCN8A (0.76) SCN8ASCN1ASCN5A
SCHEMBL31017726 0.77 SCN8A (1.00) SCN8ASCN1ASCN5A
SCHEMBL21955478 0.77 SCN8A (1.00) SCN8ASCN1ASCN5A
SCHEMBL21783436 0.77 SCN8A (1.00) SCN8ASCN1ASCN5A
SCHEMBL22005526 0.77 SCN1A (0.79) SCN8ASCN1ASCN5A
SCHEMBL23227566 0.76 SCN1A (0.74) SCN8ASCN1ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638879-B Heteroaryl substituted sulfonamide compounds and their use as therapeutic agents 泽农医药公司 2024-06-18 CN claimed
CN-112638879-B Heteroaryl substituted sulfonamide compounds and their use as therapeutic agents 泽农医药公司 2024-06-18 CN disclosed