Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 2/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 5/20 | 0.34 |
| ▸ | HTR2B | P41595 | 5/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329305 | 0.76 | CD44 (0.56) | CD44PNMTMAOBHTR2C | |
| Hydrochloric Acid SCHEMBL21326092 | 0.74 | CD44 (0.54) | CD44PNMTMAOBHTR2C | |
| Hydrochloric Acid SCHEMBL2808299 | 0.74 | CD44 (0.54) | CD44PNMTMAOBHTR2C | |
| Hydrochloric Acid SCHEMBL29586472 | 0.74 | CD44 (0.54) | CD44PNMTMAOBHTR2C | |
| SCHEMBL17021262 | 0.74 | PRCP (0.51) | CD44ASIC3PNMTMAOBHTR2A | |
| SCHEMBL30519159 | 0.74 | PRCP (0.51) | CD44ASIC3PNMTMAOBHTR2A | |
| Hydrochloric Acid SCHEMBL27077371 | 0.73 | PRCP (0.50) | CD44ASIC3HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL29893369 | 0.73 | PRCP (0.50) | CD44ASIC3HTR2AHTR2CHTR2B | |
| SCHEMBL25431215 | 0.71 | P2RY1 (0.48) | CD44ASIC3PNMTMAOBP2RY1 | |
| SCHEMBL31022094 | 0.71 | CD44 (0.44) | CD44ASIC3PNMTMAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4654969-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024159067-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2024-08-02 | — | — | WO | disclosed |