Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.56 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 5/20 | 0.48 |
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29511056 | 0.93 | ERAP2 (0.58) | ERAP2ACELTA4HECE1ERAP1 | |
| SCHEMBL29903070 | 0.93 | ERAP2 (0.56) | ERAP2ACELTA4HECE1ERAP1 | |
| SCHEMBL31239738 | 0.93 | ERAP2 (0.54) | ERAP2ACEECE1IL1RNERAP1 | |
| SCHEMBL30628999 | 0.92 | ACE (0.57) | ACELTA4HECE1KDM4EMEN1 | |
| SCHEMBL29577528 | 0.92 | ACE (0.57) | ACELTA4HECE1KDM4EMEN1 | |
| SCHEMBL29973876 | 0.92 | ACE (0.57) | ACELTA4HECE1KDM4EMEN1 | |
| SCHEMBL30628987 | 0.92 | ACE (0.57) | ACELTA4HECE1KDM4EMEN1 | |
| SCHEMBL31259940 | 0.92 | ACE (0.57) | ACELTA4HECE1KDM4EMEN1 | |
| SCHEMBL31259938 | 0.92 | ACE (0.57) | ACELTA4HECE1KDM4EMEN1 | |
| SCHEMBL7046020 | 0.91 | ACE (0.60) | ACELTA4HECE1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118460519-A | Amidase mutant and application thereof | 台州学院 | 2024-08-09 | — | — | CN | disclosed |