SCHEMBL31023720

SCHEMBL31023720

COc1cc(-n2cc(C(=O)O)cn2)ncc1C#N

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 8/20 0.55
XDH P47989 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31023519 0.85 KDM4E (0.45) EGLN1XDH
SCHEMBL17472795 0.82 EGLN1 (0.67) EGLN1XDH
SCHEMBL17472859 0.81 EGLN1 (0.51) EGLN1XDH
SCHEMBL17472791 0.81 EGLN1 (0.53) EGLN1XDH
SCHEMBL17472808 0.81 EGLN1 (0.65) EGLN1XDH
SCHEMBL17472762 0.80 EGLN1 (0.55) EGLN1XDH
SCHEMBL17472831 0.79 EGLN1 (0.57) EGLN1XDH
SCHEMBL31023594 0.79 SMN1; SMN2 (0.49) EGLN1
SCHEMBL17472792 0.79 EGLN1 (0.53) EGLN1XDH
SCHEMBL17472869 0.77 EGLN1 (0.69) EGLN1XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260027096-A1 PHD INHIBITORS UNIV OXFORD INNOVATION LTD (GB) 2026-01-29 US disclosed
EP-4655288-A1 PHD INHIBITORS Oxford University Innovation Limited (GB) 2025-12-03 EP disclosed
EP-4655294-A1 PYRAZOLE DERIVSTIVES AS PHD INHIBITORS Oxford University Innovation Limited (GB) 2025-12-03 EP disclosed
WO-2024157019-A1 PHD INHIBITORS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2024-08-02 WO disclosed
WO-2024157014-A1 PYRAZOLE DERIVSTIVES AS PHD INHIBITORS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2024-08-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260027096-A1 PHD INHIBITORS HIF1AN, HIF1A, EGLN1 EGLN1 3/4885XDH 1026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.