Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10845738 | 1.00 | SLC5A2 (0.46) | SLC5A2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL700254 | 0.86 | CYP3A4 (0.40) | SLC5A2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL12188952 | 0.82 | PARP1 (0.44) | SLC5A2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL10843817 | 0.82 | SLC5A2 (0.43) | SLC5A2CYP3A4CYP2D6TAAR1CYP1A2 | |
| SCHEMBL18648047 | 0.78 | TAAR1 (0.47) | SLC5A2CYP3A4CYP2D6TAAR1GAA | |
| SCHEMBL21514918 | 0.78 | SLC5A2 (0.38) | SLC5A2CYP3A4CYP2D6RAB9ATAAR1 | |
| SCHEMBL22356500 | 0.78 | MIF (0.40) | SLC5A2CYP3A4TAAR1ALDH1A1CYP1A2 | |
| SCHEMBL1721517 | 0.78 | SLC5A2 (0.38) | SLC5A2CYP3A4TAAR1ALDH1A1CYP1A2 | |
| SCHEMBL11696212 | 0.78 | CYP4F2 (0.38) | CYP3A4CYP2D6NPC1RAB9ABAD | |
| SCHEMBL30792604 | 0.76 | CYP3A4 (0.55) | SLC5A2CYP3A4RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665718-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | Apogee Pharmaceuticals, Inc. (CA) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024168426-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | APOGEE PHARMACEUTICALS, INC. (CA) | 2024-08-22 | — | — | WO | disclosed |