Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | RORC | P51449 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16212149 | 1.00 | KDM1A (0.54) | KDM1AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL16211989 | 0.89 | KDM1A (0.53) | KDM1AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL16211878 | 0.87 | KDM1A (0.56) | KDM1AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL16211816 | 0.87 | KDM1A (0.56) | KDM1AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL17637718 | 0.87 | KDM1A (0.56) | KDM1AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL19361025 | 0.87 | KDM1A (0.56) | KDM1AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL34473717 | 0.86 | KDM1A (0.55) | KDM1AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL7514411 | 0.85 | KDM1A (0.54) | KDM1AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL29308992 | 0.84 | KDM1A (0.61) | KDM1AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL7514544 | 0.84 | KDM1A (0.53) | KDM1AMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173514-A1 | AMIDE AND ESTER-SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS | IDEAYA BIOSCIENCES, INC. (US) | 2024-08-22 | — | — | WO | disclosed |