SCHEMBL31024642

SCHEMBL31024642

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 11/20 0.51
▸ NPY1R P25929 6/20 0.51
▸ NPY2R P49146 4/20 0.51
▸ NPY5R Q15761 4/20 0.51
▸ GNAI3 P08754 1/20 0.45
▸ GNAO1 P09471 1/20 0.45
▸ GNAI1 P63096 1/20 0.45
▸ FOLH1 Q04609 1/20 0.44
▸ GSR P00390 1/20 0.43
▸ SIRT6 Q8N6T7 1/20 0.41
▸ SIRT1 Q96EB6 1/20 0.41
▸ NOD1 Q9Y239 1/20 0.41
▸ NRP1 O14786 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31448334 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL31694502 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL32684535 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL31694501 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL15263305 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL31024643 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL15263299 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL8144504 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL8144510 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL29380690 1.00 NPY4R (0.51) NPY4RNPY1RNPY2RNPY5RGNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665754-A1 GLYCOSYLATED POLYPEPTIDES Eli Lilly and Company (US) 2025-12-24 — — EP disclosed
WO-2024173266-A1 GLYCOSYLATED POLYPEPTIDES ELI LILLY AND COMPANY (US) 2024-08-22 — — WO disclosed
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