Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.46 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.43 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.43 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.43 |
| ▸ | SALL4 | Q9UJQ4 | 1/20 | 0.43 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31025888 | 0.83 | CRBN (0.53) | CRBNIKZF2CSNK1A1IKZF1 | |
| SCHEMBL20235032 | 0.80 | CRBN (0.49) | CRBNDDB1IKZF2CSNK1A1GSPT1 | |
| SCHEMBL29583366 | 0.80 | IKZF2 (0.63) | CRBNDDB1IKZF2IKZF1 | |
| SCHEMBL20046085 | 0.80 | IKZF2 (0.63) | CRBNDDB1IKZF2IKZF1 | |
| SCHEMBL30984814 | 0.80 | CRBN (0.46) | CRBNDDB1IKZF2CSNK1A1GSPT1 | |
| SCHEMBL20442592 | 0.79 | IKZF2 (0.52) | CRBNDDB1IKZF2CSNK1A1GSPT1 | |
| SCHEMBL31025890 | 0.79 | IKZF2 (0.70) | CRBNDDB1IKZF2IKZF1 | |
| SCHEMBL29648391 | 0.79 | IKZF2 (0.52) | CRBNDDB1IKZF2CSNK1A1GSPT1 | |
| SCHEMBL27302563 | 0.79 | IKZF2 (0.52) | CRBNDDB1IKZF2CSNK1A1GSPT1 | |
| SCHEMBL25580340 | 0.79 | IKZF2 (0.60) | CRBNDDB1IKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024162746-A1 | INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF | 한국화학연구원 | 2024-08-08 | — | — | WO | disclosed |