Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 13/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026313 | 0.90 | CNR1 (0.78) | MAPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL30995728 | 0.82 | CNR1 (0.79) | MAPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL31026328 | 0.78 | CNR1 (0.74) | MAPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL30995727 | 0.77 | CNR1 (0.77) | MAPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL15099324 | 0.76 | CNR1 (0.90) | CNR1CNR2 | |
| SCHEMBL20408204 | 0.76 | CNR1 (0.91) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL15094521 | 0.76 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL15094519 | 0.76 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL30571176 | 0.76 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL15099336 | 0.76 | CNR1 (1.00) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420514-A | Method for synthesizing 3- (2-nitro-1-aryl) -1H-indole derivative by using cyclopentadienyl titanium/Bronsted acid in synergistic catalysis mode | 宁夏师范学院 | 2024-08-02 | — | — | CN | disclosed |