Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PER2 | O15055 | 2/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21957282 | 1.00 | ATM (0.46) | ATMKMT2ALMNAMEN1HCRTR1 | |
| SCHEMBL31563541 | 0.79 | ATM (0.42) | ATMKMT2ALMNAMEN1HCRTR1 | |
| SCHEMBL31563182 | 0.79 | ATM (0.42) | ATMKMT2ALMNAMEN1HCRTR1 | |
| SCHEMBL13925420 | 0.78 | ATM (0.67) | ATMKMT2AMEN1HCRTR1KDM4E | |
| SCHEMBL30901264 | 0.77 | ATM (0.43) | ATMKMT2AMEN1HCRTR1KDM4E | |
| SCHEMBL21978883 | 0.77 | ATM (0.43) | ATMKMT2AMEN1HCRTR1KDM4E | |
| SCHEMBL8140534 | 0.76 | ATM (0.53) | ATMKMT2AMEN1HCRTR1KDM4E | |
| SCHEMBL31563362 | 0.76 | KDM4E (0.64) | ATMKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL13914147 | 0.74 | ATM (0.58) | ATMKMT2ALMNAMEN1HCRTR1 | |
| SCHEMBL31563196 | 0.73 | AR (0.34) | ATMKMT2ALMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462635-A | Quinoline derivatives as alpha 4 beta 7 integrin inhibitors | 吉利德科学公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-112969687-B | Quinoline derivatives as a4 b 7 integrin inhibitors | 吉利德科学公司 | 2024-08-23 | — | — | CN | disclosed |