SCHEMBL31028388

SCHEMBL31028388

COc1ccnc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)c3c(c12)OCCC3

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KAT7 O95251 20/20 0.58
KAT6A Q92794 20/20 0.58
KAT6B Q8WYB5 16/20 0.58
KAT5 Q92993 11/20 0.58
KAT8 Q9H7Z6 11/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30360856 1.00 KAT7 (0.58) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25561979 1.00 KAT7 (0.58) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25564881 0.98 KAT6A (0.59) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30360811 0.98 KAT6A (0.59) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25562273 0.96 KAT7 (0.59) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30360813 0.96 KAT7 (0.59) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25045967 0.92 KAT7 (0.68) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31028384 0.92 KAT7 (0.68) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25562122 0.90 KAT7 (0.67) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31028390 0.89 KAT6A (0.53) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118556053-A Lysine acetyl transferase 6A (KAT 6A) inhibitor and application thereof 英矽智能科技知识产权有限公司 2024-08-27 CN disclosed